In 2024, the Winn Family Foundation engaged the Science Philanthropy Alliance to explore how strategic science philanthropy could accelerate grassland restoration, an underfunded yet vital area of environmental science. The Foundation was particularly interested in understanding where basic research could unlock scalable solutions for climate resilience, biodiversity conservation, and sustainable land use.
To support this exploration, the Alliance developed a custom briefing that mapped the landscape of grassland restoration science. The report synthesized ecological research priorities, emerging scientific questions, and practitioner-informed insights across a range of disciplines, including fire ecology, soil microbiomes, grazing dynamics, and traditional ecological knowledge.
The Alliance also identified opportunities for scientific leadership: outlining key institutions and experts active in the field and showcasing how private philanthropy—including Allen Family Philanthropies and the Doris Duke Foundation—is catalyzing applied research and ecosystem-scale implementation efforts. The report highlighted the unique role philanthropy can play in addressing major restoration challenges, such as conflicting land use priorities, gaps in ecological data, and underinvestment in long-term monitoring.
By grounding the Foundation’s interest in a rigorous scientific framework, the Alliance helped the Winn Family Foundation clarify its potential role in this complex and fast-evolving field. This work laid the foundation for future investments in science that not only inform on-the-ground action but also shape the broader field of ecosystem restoration for years to come.
In 2023, the Prebys Foundation turned to the Science Philanthropy Alliance for strategic and operational support in developing a new medical research initiative. The Foundation sought to fund exceptional early- and mid-career researchers in San Diego—particularly those from groups historically underrepresented in biomedical research—whose work had the potential to drive transformative health outcomes.
The Alliance partnered closely with Prebys Foundation staff to co-design the program from the ground up. Over the course of several months, the Alliance helped define the program’s goals, refine selection criteria, design and implement the RFP and review process, and advise on nominee evaluation and the external review process. The result was the Prebys Research Heroes Award Program: a $7 million initiative announced in 2024 that awarded fourteen $500,000 grants to scientists working on urgent health challenges—from Alzheimer’s and cancer to infectious disease and maternal health.
The Alliance provided hands-on program office support throughout the initiative, including outreach to local institutions, managing the peer review process, developing program communications, and advising on metrics and evaluation. The initiative also benefited from a collaborative working model that included the consulting firm Open Impact, which worked alongside the Alliance and the Foundation to ensure the program was both rigorous and responsive to the needs of the local research ecosystem.
By investing in talent across institutions such as the Salk Institute, UC San Diego, Scripps Research, and San Diego State University, the Prebys Foundation has elevated a cohort of diverse scientific leaders while strengthening San Diego’s role as a hub for medical innovation. The Alliance’s involvement helped ensure that the program was grounded in practices from across science philanthropy—and built to generate long-term impact.
As Grant Oliphant, CEO of the Foundation, explained, “Our program is designed to empower brilliant researchers with the means to pursue cutting-edge research that promises to tackle some of the most challenging diseases facing our world today.”
Elaine and Stuart Sevier, council members of the Shanahan Family Foundation, bring to the Foundation a bold and future-oriented vision that reimagines public engagement with science. Their leadership catalyzed the launch of the Independent Media Initiative (IMI) in 2022, a nonprofit that empowers digital creators to explore and share science with rigor, creativity, and cultural fluency—reaching broad new audiences across the country.
From IMI's inception, the Science Philanthropy Alliance has served as a close collaborator, helping the Seviers think strategically about how to fund this emerging field and inspire peer foundations to join the effort. In IMI's first year, the Alliance helped the organization foster a partnership with the John Templeton Foundation—an early validation of the Seviers’ vision that established the first annual IMI Fest as a hub for leading educational and artistic creators on the internet.
In 2024, the Alliance helped facilitate an exciting new collaboration between IMI and the Alfred P. Sloan Foundation. Sloan, seeking to broaden its reach through digital media, found a mission-aligned partner in IMI. Together, they launched the Sloan Science Prizes for Youtube, supporting science creators who combine intellectual depth with mainstream appeal.
The need for this work is urgent and clear. With 2.7 billion monthly active users, YouTube is the second most visited website in the world and reaches over 80% of U.S. adults—across political lines, income levels, and geographic divides. Americans now watch YouTube as much or more than television, and a single video's reach can rival the combined annual attendance of U.S. science museums. Yet despite its massive influence, YouTube remains largely overlooked by philanthropy. Supporting evidence-based creators on platforms people already trust is one of the most effective ways for funders to ensure science remains visible, relevant, and accessible.
Throughout, the Alliance has acted as a trusted advisor and connector—identifying moments of strategic alignment, opening doors, and lending credibility to a bold new model for science communications. As digital platforms reshape how people engage with science, IMI offers an inspiring blueprint for how philanthropy can meet audiences where they are and invest in a media ecosystem that is credible, inclusive, and built for the future.
The future of scientific discovery depends on supporting the next generation of researchers and fostering a culture of public engagement and trust in science. The Alliance has played a key role in helping funders recognize the importance of investing in early-career scientists, mentorship programs, and fellowships that sustain an inclusive and innovative research community. By supporting promising researchers at critical career stages, philanthropy can help ensure that groundbreaking ideas are pursued and developed into transformative discoveries.
Beyond supporting researchers, the Alliance has worked to build a more resilient future for science by engaging the public and strengthening trust in scientific institutions. Science philanthropy has a role to play in making research more transparent, accessible, and responsive to societal needs. Through strategic investments in public outreach, science communication, and civic engagement programs, the Alliance has helped funders support initiatives that connect scientific progress with real-world impact.