Dear Partners,

What started as a collaboration among six visionary foundations has evolved into a vibrant alliance of 40 members and a global community of funders, scientists, and advisors committed to advancing discovery science for the benefit of humanity.

Ten years ago, the Science Philanthropy Alliance began as an ambitious idea: to inspire and equip philanthropists to support basic scientific research. What started as a collaboration among six visionary foundations has evolved into a vibrant alliance of 40 members and a global community of funders, scientists, and advisors committed to advancing discovery science for the benefit of humanity.

As we reflect on the past decade, we are proud of what we’ve accomplished together. The Alliance has advised hundreds of philanthropists, influenced more than $4 billion in science funding, and helped shape a field that is more strategic, collaborative, and impactful than ever before. In 2024 alone, we completed over 100 advisory projects and influenced more than $170 million in new funding to science.

We share this report at a time of significant change in the scientific research landscape. In recent months, proposed federal cuts to major science agencies and shifts in national funding priorities have raised urgent questions about the future of the U.S. research enterprise. These developments underscore a reality the Alliance has long recognized: philanthropy has a vital role to play—not as a replacement for public funding, but as a source of flexible, long-term support that sustains discovery and enables bold new directions in research.

In this environment, the Alliance’s mission has never been more critical. By connecting committed philanthropists with high-impact opportunities, and translating vision into strategy, we help ensure that transformative science continues to thrive.

As we look ahead to our second decade, we are energized by what’s possible. Thank you for being part of this journey. Together, we can unlock the potential of science philanthropy to transform lives and our shared future.